Place your tongue tip near the roof of your mouth behind your top teeth. Push air through the narrow gap. No voicing.

Americans pronounce synthesizes as SIHN-thuh-sahy-zuhz (/ˈsɪnθəˌsaɪzəz/). Stress falls on the first syllable — keep everything else short and quick. You'll hear it in sentences like "The literature review synthesizes findings from multiple studies".
Record yourself saying "synthesizes" and play it back. The mic stays on your device — nothing's uploaded.
4 syllables, 10 sounds. Tap a syllable to jump to its row, then explore each sound's mouth shape and how it's made.
Place your tongue tip near the roof of your mouth behind your top teeth. Push air through the narrow gap. No voicing.

Drop your jaw slightly with relaxed lips. Touch the tongue tip behind the bottom front teeth and arch the top-front toward the roof.

Touch the tip or front edge of your tongue to the roof of your mouth behind your teeth. Air flows through your nose.

Click any sentence to see the full breakdown — every link, every reduction, every flap-T.
The textbook way isn't wrong — it's just not how anyone actually says it.
Stress falls on the first syllable, not the others. Stretch SIHN — keep everything else short and quick.
Don't pronounce the first syllable too fully. The unstressed syllable reduces to a schwa — the lazy "uh" sound — in casual speech.