How to pronounce mitosis in American English

IPA /maɪˈtoʊsəs/ Syllables 3 · mahy·toh·suhs Stress 2nd syllable
mahy·TOH·suhs
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Americans pronounce mitosis as mahy-TOH-suhs (/maɪˈtoʊsəs/). The unstressed syllable reduces to a lazy schwa — almost a quick "uh" — instead of being pronounced fully. Stress falls on the second syllable — keep everything else short and quick.

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Common mistakes

Stressing the wrong syllable.

Stress falls on the second syllable, not the others. Stretch TOH — keep everything else short and quick.

Pronouncing the unstressed syllable too fully.

Don't pronounce the second syllable too fully. The unstressed syllable reduces to a schwa — the lazy "uh" sound — in casual speech.

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In real conversation

Hear "mitosis" in the wild.

Click any sentence to see the full breakdown — every link, every reduction, every flap-T.

"Cells divide and replicate through a process called mitosis."
SEHLZ duh·VAHYD and REH·pluh·kayt throo uh PRAH·sehs KAHLD mahy·TOH·suhs
Watch out

Common pronunciation mistakes in American English.

The textbook way isn't wrong — it's just not how anyone actually says it.

01

Stressing the wrong syllable.

Stress falls on the second syllable, not the others. Stretch TOH — keep everything else short and quick.

MAHY·toh·SUHSmahy·TOH·suhs
02

Pronouncing the unstressed syllable too fully.

Don't pronounce the second syllable too fully. The unstressed syllable reduces to a schwa — the lazy "uh" sound — in casual speech.

mahy·TOH·SUHSmahy·TOH·suhs
Questions

Questions people ask about this.

How is "mitosis" stressed in American English?
Stress falls on the second syllable — say "TOH" with a longer, fuller vowel and keep every other syllable short and quick. The respell "mahy-TOH-suhs" marks the stressed syllable in capitals so the rhythm is easy to read at a glance.
Why does the third syllable in "mitosis" reduce to "uh"?
Unstressed syllables in American English collapse toward a schwa — a lazy, neutral "uh" sound. The full vowel is what textbooks teach, but in actual American speech every unstressed vowel reduces. The respell "mahy-TOH-suhs" shows the reduced form so you can hear the casual rhythm directly.
Is the American pronunciation of "mitosis" different from British English?
American English uses different vowel shapes, a relaxed retroflex R, and connected-speech tricks like flap-T and glottal-stop T that British Received Pronunciation generally avoids. The respell "mahy-TOH-suhs" reflects the casual American form; British dictionaries typically print a citation form with crisper consonants and different vowel choices.

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